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Kelly Sherwood is terrorized by a man with an asthmatic voice who plans to use her to steal $100,000 from the bank where she works. He threatens to kill her teenage sister Toby, if she tells the police. However she manages to contact F.B.I. agent Ripley.
When terrorist action releases a secret government virus in the Houston Federal building, the employees become aggressive and homicidal. Federal officials quarantine the building to wipe out the infected and control the story, but a small group of uninfected are fighting to get out.
A group of friends, in dire need of cash, find themselves at a secluded medical trial retreat in what seems like an easy way to earn money but quickly turns into their worst nightmare. Under the guise of a harmless experiment run by the enigmatic Dr. Feldman, they are about to face a horror they never imagined. Unbeknownst to them, Dr. Feldman has unleashed a new terror: a swarm of genetically engineered killer flies, with an insatiable thirst for human blood.
1982: The survivors of a series of brutal killings in a small town thought mass murderer Alex Black was dead and buried after the townspeople put an end to him. But teenagers experimenting with the occult awaken the monster from his grave and he begins another rampage of terror with his favorite tool, a pickaxe. Only those who have faced him before have any chance of stopping Alex Black once and for all.
Year 2116—The Japanese government begins to export the Sibyl System unmanned drone robots to troubled countries, and the system spreads throughout the world. A state in the midst of a civil war, SEAUn (the South East Asia Union), brings in the Sibyl System as an experiment. Under the new system, the coastal town of Shambala Float achieves temporary peace and safety. But then SEAUn sends terrorists to Japan. They slip through the Sibyl System and then attack from within. The shadow of a certain man falls on this incident. In charge of the police, Tsunemori travels to Shambala Float to investigate. The truth of justice on this new ground will become clear.
1945: The red army stands at the gates of Berlin. In their desperation the Nazis turn to the most obscure Scientists. Through cruel experiments a new secret Weapon has been created – unstoppable and alive. A Russian attack destroys the lab, but the weapon – buried underneath the ruins – is immortal. Lost in time, it lurks in the darkness, only to return again. 2012: Punk-Rock legend Spike Jones leads a group of friends into the ruins of the old Nazi Lab. The complex shall be cleaned up for the reunion concert of his band. Believing they would help a poor soul, they free the beast from its prison. But the creature of the Nazis does not know about thankfulness. Again the smell of blood fills the old laboratories and screams of terror echo through the darkness. As now, the Werewolf starts his war against humanity.
Horrifying shocker as a biological experiment goes haywire when meat-eating mutant roaches invade an island community, terrorizing a peaceful New England fishing village and hideously butchering its citizens.
Psychotic Angela is itching to do what she does best: slaughter dozens of teenage campers. As luck would have it, the previous site of her murders has been renamed and converted into an experimental summer camp meant to bring together privileged and lower-class teens. On the day the youths are boarding the buses to camp, Angela runs over a potential camper with a garbage truck and assumes her identity. Once she has infiltrated the camp, the real terror begins.
Five female filmmakers en route to screen their new horror film in Los Angeles, experience their own real life terror when they cross paths with deranged scientist hellbent on using them for his twisted experiments.